专利名称：Therapeutic agents and methods of use
thereof for the modulation of angiogenesis
发明人：Gary L. Olson,Christopher Self,Lily
Lee,Charles Michael Cook,Jens Birktoft,BarryMorgan,Christopher C. Arico-Muendel
申请号：US10001945申请日：20011101
公开号：US20020151493A1公开日：20021017
摘要：The present invention provides angiogenesis inhibitor compounds comprising aMetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositionscomprising the angiogenesis inhibitor compounds and a pharmaceutically acceptablecarrier. The present invention also provides methods of treating an angiogenic disease,e.g., cancer, in a subject by administering to the subject a therapeutically effective amountof one or more of the angiogenesis inhibitor compounds of the invention.
申请人：PRAECIS PHARMACEUTICALS INC.
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